The Town of Lake Santeetlah is a town in Graham County, North Carolina, United States, six miles (10 km) north of Robbinsville and within fifteen miles (24 km) of the Great Smoky Mountains National Park on a peninsula surrounded by Lake Santeetlah—which in turn is largely surrounded by Nantahala National Forest. The town has more than two hundred residences, many of them second homes owned by permanent residents of Florida and Georgia. The town was organized in 1989 as Santeetlah; in 1999, it changed its name to Lake Santeetlah. The full-time population was 67 at the 2000 census.

Santeetlah Lake and the Cheoah District of the Nantahala National Forest which surrounds it provide exceptional recreational opportunities. The lake has a variety of fish including smallmouth bass, largemouth bass, walleye, crappie, bream, and lake trout. Santeetlah Marina is the only full-service marina on a lake that has 76 miles (122 km) of shoreline. There are more than fifty primitive campsites scattered around the lake that include a picnic table and fire ring.

There are over 200 miles (320 km) of hiking trails in the Cheoah District, and one can hike about eight miles (13 km) from Lake Santeetlah to the Appalachian Trail. Approximately a mile from the town is Cheoah Point Recreation Area, which has developed swimming, camping, and picnic facilities as well as a boat ramp.